Published Research

Research funded by PDLF and published in Peer-reviewed Scientific Literature

Lynas C, Hurlock NJ, Copplestone JA, Prentice AG.
PCR-SSP:  A cautionary tale and an update of the Bein Primer Mixes.
Tissue Antigens 1994; 43: 206-207.

Lynas C, Hurlock NJ, Copplestone JA, Prentice AG, McGonigle RJS
HLA-DR typing for kidney transplants: Advantage of polymerase chain reaction with sequence specific primers in a routine hospital laboratory.
J.Clin.Pathol. 1994; 47: 609-612.

Mainou-Fowler T, Craig VA, Copplestone JA, Hamon MD, Prentice AG.
Interleukin-5 (IL-5) increases spontaneous apoptosis of B-cell chronic lymphocytic leukemia cells in vitro independently of bcl-2 expression and is inhibited by IL-4.
Blood 1994; 84:2297-2304.

Mainou-Fowler T, Craig VA, Copplestone A, Hamon MD, Prentice AG
Effect of anti-APO1 on spontaneous apoptosis of B cells in chronic lymphocytic leukaemia: the role of bcl-2 and interleukin 4.
Leuk Lymphoma 1995; 19: 301-308.

Mainou-Fowler T, Copplestone JA, Hamon M.D, Prentice A.G.
Effects of Interleukins on the Proliferation and Survival of B-Chronic Lymphocytic Leukaemia Cells.
J.Clin.Pathol 1995; 48: 482-487.

Foster AM, Prentice AG, Copplestone J.A, Cartwright RA, Ricketts C.
The distribution of leukaemia in association with domestic water quality in South West England.
Eur J Cancer Prev 1997; 6: 11- 19

Cytoplasmic interleukin-4 (IL-4) and surface IL-4 receptor expression in patients with B-cell lymphocytic leukemia.
Kaminski A, Demaine A, Prentice A.
Blood. 1998; 92: 2188-2189.

Goddard RV, Prentice AG, Copplestone JA, Kaminski ER
Generation in vitro of B-cell chronic lymphocytic leukaemia-proliferative and specific HLA class-II-restricted cytotoxic T-cell responses using autologous dendritic cells pulsed with tumour cell lysate.
Clin Exp Immunol 2001; 126:16-28

Analysis of the expression of critical activation/interaction markers on peripheral blood T cells in B-cell chronic lymphocytic leukaemia: evidence of immune dysregulation.
Scrivener S, Kaminski ER, Demaine A, Prentice AG.
Br J Haematol. 2001; 112: 959-964.

Monk SE Duckworth AW, Farrugia J, Copplestone JA, Rule SAJ.
Allelic discrimination of Factor V Leiden using the GeneAmp 5700 sequence detection system.
Thromb Haemost 2002; 88:1071-1072.

Goddard R, Prentice A, Copplestone A, Kaminski E
A study of the proteins responsible for stimulating B-CLL-specific T-cell responses by autologous dendritic cells pulsed with tumour cell lysate.
Hematol J 2003; 4: 271-276.

Abnormal T-cell function in B-cell chronic lymphocytic leukaemia.
Scrivener S, Goddard RV, Kaminski ER, Prentice AG.
Leuk Lymphoma. 2003; 44: 383-389.

Dendritic cells and their potential therapeutic role in haematological malignancy.
Kaminski ER, Goddard RV, Prentice AG.
Leuk Lymphoma. 2003; 44: 1657-1666.

Goddard RV, Prentice AG, Copplestone JA, Kaminski ER
In vitro dendritic cell induced T cell responses to B cell chronic Lymphocytic enhanced by IL-15 and dendritic cell- B-CLL electrofusion hybrids.
Clin Exp Immunol 2003; 131: 82-89.

Richardson SJ, Mathews C, Catherwood MA, Alexander HD, Carey BS, Farrugia J, Gardiner A, Mould S, Oscier D, Copplestone JA, Prentice AG.
ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL).
Blood 2006; 107: 3584-92.